1.
Indian J Pediatr
;
2001 Jun; 68(6): 563-6
Article
in English
| IMSEAR
| ID: sea-81177
ABSTRACT
Glanzmann's thrombasthenia (GT) is an uncommon cause of bleeding in children. We diagnosed two siblings as having GT on the basis of flow cytometric studies. Both had cutaneous bleedings and epistaxis since early childhood. Hematological investigations revealed prolonged bleeding time and a normal platelet count. Both the patients had absence of aggregation of platelets with the agonist adenosine diphosphate. Absence of the GPIIb/IIIa receptor was confirmed by flow cytometry. A short review of the disorder is presented.
Subject(s)
Child, Preschool , Diagnosis, Differential , Female , Flow Cytometry , Hemorrhagic Disorders/genetics , Humans , Male , Platelet Glycoprotein GPIIb-IIIa Complex/genetics , Thrombasthenia/diagnosis
2.
J Postgrad Med
;
1979 Jul; 25(3): 183-5
Article
in English
| IMSEAR
| ID: sea-115736